Study on the clinical effect of blue light therapy on neonatal jaundice
新生儿黄疸蓝光治疗临床效果研究

摘要

目的 研究分析新生儿黄疸治疗过程中持续蓝光照射治疗及间歇蓝光照射治疗的作用。方法 本次实验跨越2020年4月至2021年8月这一时间段，研究人员对200例新生儿黄疸患儿进行研究。在本次实验中，研究人员将所选患者按照双盲对照原则分组，对照组所选100例患儿采用持续蓝光照射治疗，实验组所选100例患儿采用间歇蓝光照射治疗，记录对照组及实验组患儿不良反应（腹泻、皮疹、发热）出现情况、肝功能指标（TBil、ALT、ALP），并加以比较分析。结果 对照组所选患儿中共计26人出现不良反应，占所选患儿人数的比例为26.00%，实验组中出现不良反应的患儿人数为6人，占比为6.00%，分析两组患儿不良反应出现概率相关数据，差异较大，（p＜0.05）；对照组及实验组所选患儿在治疗后肝功能指标方面差异突出，TBil、ALT、ALP均有着较为明显的差距，（p＜0.05）。结论 在新生儿黄疸治疗过程中间歇蓝光照射治疗有着不俗的表现，效果远远优于持续蓝光照射治疗，其在减少不良反应、改善患儿肝功能指标方面成绩显著。

Abstract

Objective: To study and analyze the effects of continuous blue light irradiation and intermittent blue light irradiation in the treatment of neonatal jaundice.
Methods: This experiment spanned the period from April 2020 to August 2021. Researchers conducted a study on 200 children with neonatal jaundice. In this experiment, the researchers grouped the selected patients according to the principle of double-blind control. 100 children in the control group were treated with continuous blue light irradiation, and 100 children in the experimental group were treated with intermittent blue light irradiation, and the control group was recorded The occurrence of adverse reactions (diarrhea, rash, fever) and liver function indexes (TBil, ALT, ALP) of children in the experimental group and the experimental group were compared and analyzed.
Results: A total of 26 children in the control group had adverse reactions, accounting for 26.00% of the number of selected children. In the experimental group, the number of children with adverse reactions was 6, accounting for 6.00%. Analysis of the two There is a big difference in data related to the occurrence probability of adverse reactions in children in the group, (p<0.05); the selected children in the control group and the experimental group have prominent differences in liver function indexes after treatment, and there are obvious gaps in TBil, ALT, and ALP. , (P<0.05).
Conclusion  : Intermittent blue light irradiation has a good performance in the treatment of neonatal jaundice, and the effect is far better than continuous blue light irradiation. It has significant results in reducing adverse reactions and improving liver function indicators in children.