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当前位置：国际儿科研究杂志 > 2024年 4卷 (1)期

Open Access Article

International Journal of Pediatrics Research. 2024; 4: (1) ; 11-17 ; DOI: 10.12208/j.ijped.20240003.

Prevalence and influencing factors of hyperuricemia in children and adolescents aged 1-14 yearsin baotou city
包头市1-14岁儿童青少年高尿酸血症患病率及影响因素分析

作者： 施睿, 经鑫爱 *

内蒙古科技大学包头医学院第一附属医院儿科内蒙古包头

*通讯作者：经鑫爱,单位：内蒙古科技大学包头医学院第一附属医院儿科内蒙古包头；

发布时间: 2024-04-25 总浏览量: 209

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摘要

目的了解包头市儿童青少年高尿酸血症的患病情况及相关影响因素，为高尿酸血症的防治提供科学依据。方法随机选取2022年9月至2023年9月于包头医学院第一附属医院儿科门诊体检的1768名1-14岁儿童青少年为研究对象，收集其人口学信息、体格检查、实验室检查和生活饮食习惯等资料，对儿童青少年HUA的患病情况进行回顾性研究，并通过多因素logistic逐步回归探索影响高尿酸血症患病率的相关因素。结果高尿酸血症总体患病率为35.46%，男生（46.21%）高于女生（25.36%），差异有统计学意义（P＜0.001）；多因素logistic逐步回归示年龄、性别、血糖升高、血脂异常、TG、TC、屏幕时间、睡眠时间、含糖饮料摄入过多，盐摄入过多和高尿酸血症家族史是发生高尿酸血症的独立危险因素（P＜0.001），HDL是高尿酸血症的保护因素（P＜0.001）。结论包头市儿童青少年高尿酸血症患病率处于较高水平，其中男孩患病率高于女孩；改善不良饮食习惯及生活方式将利于儿童青少年HUA的发生与发展。

关键词： 包头市；儿童青少年；高尿酸血症；影响因素

Abstract

Objective To understand the prevalence and related influencing factors of hyperuricemia in children and adolescents in Baotou City, and to provide scientific basis for the prevention and treatment of hyperuricemia.
Methods 1768 children and adolescents aged 1-14 who underwent physical examinations in the pediatric outpatient department of the First Affiliated Hospital of Baotou Medical College from September 2022 to September 2023 were randomly selected as the research subjects. Demographic information, physical examination, laboratory examination, and dietary habits were collected to retrospectively study the prevalence of hyperuricemia in children and adolescents. Multiple logistic regression was used to explore the relevant factors affecting the prevalence of hyperuricemia.
Results The overall prevalence of hyperuricemia was 35.46%, with boys (46.21%) being higher than girls (25.36%), and the difference was statistically significant (P<0.001); Multivariate logistic stepwise regression showed that age, gender, elevated blood sugar levels, dyslipidemia, TG, TC, screen time, sleep time, excessive intake of sugary drinks, excessive salt intake, and family history of hyperuricemia were independent risk factors for hyperuricemia (P<0.001), while HDL was a protective factor for hyperuricemia (P<0.001).
Conclusion The incidence of hyperuricemia among children and adolescents in Baotou City is at a high level, with boys having a higher incidence than girls; Improving unhealthy eating habits and lifestyle will be beneficial for the occurrence and development of HUA in children and adolescents.

Key words： Baotou City; Children and adolescents; Hyperuricemia; Influencing factor

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引用本文

施睿, 经鑫爱, 包头市1-14岁儿童青少年高尿酸血症患病率及影响因素分析[J]. 国际儿科研究杂志, 2024; 4: (1) : 11-17.

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