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Open Access Article

International Journal of Pediatrics Research. 2022; 2: (3) ; 28-32 ; DOI: 10.12208/j. ijped. 20220038.

Research progress on risk factors of bronchial asthma in children
儿童支气管哮喘发生危险因素的研究进展

作者: 何艳, 左艳芳*,

承德医学院附属沧州市人民医院儿科 河北沧州

*通讯作者: 左艳芳,单位:承德医学院附属沧州市人民医院儿科 河北沧州;

发布时间: 2022-10-31 总浏览量: 74

摘要

支气管哮喘是儿童时期最常见的慢性呼吸系统疾病,其以可变的气流受限和气道高反应性为特征,且发病率在不断上升。哮喘的发病与遗传、环境及宿主因素密切相关,病因及机制非常复杂。哮喘具有明显的家族聚集倾向,发病年龄越小,遗传倾向越明显,母孕期不利因素、环境中变应原接触、烟草暴露、室外及室内环境污染、宿主本身特应性体质等会增加哮喘发生的风险。由于有不同危险因素的存在,导致哮喘的发生及反复急性发作。哮喘的反复发作及长期管理给儿童、家长及社会带来了困扰。因此,了解哮喘发生的危险因素对于哮喘的诊断、个性化治疗和管理具有重要意义。本文就儿童哮喘的发生危险因素作一综述。

关键词: 儿童;支气管哮喘;危险因素;遗传;研究进展;综述

Abstract

Bronchial asthma is the most common chronic respiratory disease in childhood and is characterized by variable airflow limitation and airway hyperresponsiveness with increasing incidence. The pathogenesis of asthma is closely related to genetic, environmental and host factors, and the etiology and mechanism are very complex. Asthma has obvious familial aggregation tendency. The younger the age of onset, the more obvious the genetic tendency. The adverse factors during pregnancy, exposure to allergens in the environment, tobacco exposure, outdoor and indoor environmental pollution, and the host's own atopic constitution will increase the incidence of asthma. risks of. Due to the existence of different risk factors, the occurrence and repeated acute attacks of asthma are caused. Recurrent asthma exacerbations and long-term management cause distress to children, parents, and society. Therefore, understanding the risk factors for the development of asthma is of great significance for the diagnosis, personalized treatment and management of asthma. This article reviews the risk factors for childhood asthma.

Key words: Children; Bronchial asthma; Risk factors; hereditary; Research progress; review.

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引用本文

何艳, 左艳芳, 儿童支气管哮喘发生危险因素的研究进展[J]. 国际儿科研究杂志, 2022; 2: (3) : 28-32.